脑梗死与血脂、血糖、血尿酸水平的关系探讨

    Relationship between cerebral infarction and levels of blood lipids,blood glucose and uric acid

    • 摘要: 目的: 探讨脑梗死患者血脂、血糖、血尿酸水平变化及其临床意义。方法: 检测60例脑梗死患者的7项血脂指标以及血糖(GLU)、血尿酸(UA),并与对照组30例的检测结果进行比较。结果: 脑梗死患者的胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、载脂蛋白B (ApoB)、脂蛋白(a)Lp (a)、GLU含量均高于对照组(P<0.05~P<0.001),载脂蛋白A1(ApoA1)含量显著低于对照组(P<0.001),UA和高密度脂蛋白(HDL)含量变化差异均无统计学意义(P>0.05)。结论: TC、TG、LDL、ApoB、Lp (a)、GLU的水平升高,ApoA1下降与脑梗死均有一定关系,应重视对高血脂、高血糖的积极防治。

       

      Abstract: Objective: To explore the relationship between cerebral infarction (CI) and the levels of blood lipids, blood glucose and serum uric acid.Methods: Seven indices of serum lipids and blood glucose (GLU), serum uric acid (UA) in 60 patients with CI (patient group) and 30 cases without CI (control group) were measured and compared.Results: The serum levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), apolipoprotein B (ApoB), lipoprotein (a) Lp (a), GLU were obviously higher in the cerebral infarction group than those in the control group (P<0.05-P<0.001), but apolipoprotein A1 (Apo A1) was significantly lower (P<0.001).There was no significant difference in high-density lipoprotein (HDL) and UA levels between cerebral infarction group and control group (P>0.05).Conclusions: The results suggest that the higher levels of TC, TG, LDL, ApoB, Lp (a), GLU and lower levels of ApoA1 are related to CI to a certain extent, which indicates that it is necessary to actively control and prevent the hyperlipidemia and the high blood glucose.

       

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