汪琼, 金国玺, 裴晓艳, 于磊, 汪丽, 胡红艳, 吴凤. 内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的关系[J]. 蚌埠医学院学报, 2021, 46(8): 1000-1003. DOI: 10.13898/j.cnki.issn.1000-2200.2021.08.003
    引用本文: 汪琼, 金国玺, 裴晓艳, 于磊, 汪丽, 胡红艳, 吴凤. 内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的关系[J]. 蚌埠医学院学报, 2021, 46(8): 1000-1003. DOI: 10.13898/j.cnki.issn.1000-2200.2021.08.003
    WANG Qiong, JIN Guo-xi, PEI Xiao-yan, YU Lei, WANG Li, HU Hong-yan, WU Feng. Study on the correlation of visceral fat area, serum cystatin C with carotid arteriosclerosis in type 2 diabetes mellitus[J]. Journal of Bengbu Medical College, 2021, 46(8): 1000-1003. DOI: 10.13898/j.cnki.issn.1000-2200.2021.08.003
    Citation: WANG Qiong, JIN Guo-xi, PEI Xiao-yan, YU Lei, WANG Li, HU Hong-yan, WU Feng. Study on the correlation of visceral fat area, serum cystatin C with carotid arteriosclerosis in type 2 diabetes mellitus[J]. Journal of Bengbu Medical College, 2021, 46(8): 1000-1003. DOI: 10.13898/j.cnki.issn.1000-2200.2021.08.003

    内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的关系

    Study on the correlation of visceral fat area, serum cystatin C with carotid arteriosclerosis in type 2 diabetes mellitus

    • 摘要:
      目的探讨内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的相关性。
      方法选择2型糖尿病病人127例,根据是否发生颈动脉粥样硬化分为单纯2型糖尿病组(对照组)40例和2型糖尿病合并颈动脉硬化组(硬化组)87例,检测内脏脂肪面积、血清胱抑素C及其他指标,分析内脏脂肪面积、血清胱抑素C与2型糖尿病颈动脉硬化的相关性。
      结果单因素分析显示,硬化组年龄、体质量指数、收缩压、病程、胱抑素C、内脂肪面积均大于对照组(P < 0.05~P < 0.01);logistic回归分析显示,胱抑素C、内脏脂肪面积、年龄是2型糖尿病病人发生颈动脉硬化的危险因素。
      结论胱抑素C和内脏脂肪面积与2型糖尿病颈动脉硬化有关,可为2型糖尿病颈动脉硬化的早期诊断提供参考。

       

      Abstract:
      ObjectiveTo explore the correlation of visceral fat area and serum cystatin C with carotid atherosclerosis in type 2 diabetes mellitus.
      MethodsAccording to whether having carotid artery aterosclerosis, 127 patients with type 2 diabetes mellitus were divided into the simple diabetes mellitus group(control group, 40 cases) and type 2 diabetes mellitus complicated with carotid atherosclerosis(sclerosis group, 87 cases).The visceral fat area, serum cystatin C and other indexes were detected, and the correlation of visceral fat area and serum cystatin C with carotid atherosclerosisin type 2 diabetes mellitus were analyzed.
      ResultsThe age, body mass index, systolic blood pressure, course of disease, cystatin C and visceral fat area in sclerosis group were greater than those in control group(P < 0.05 to P < 0.01).The results of logistic regression analysis showed that the cystatin C, visceral fat area and age were the risk factors of carotid atherosclerosis in patients with type 2 diabetes mellitus.
      ConclusionsThe cystatin C and visceral fat area are related to the carotid atherosclerosis in type 2 diabetes mellitus, which may provide a reference for early diagnosis of carotid atherosclerosis in type 2 diabetes mellitus.

       

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