Abstract: Objective: To explore the role of three-way pipe in transurethral resection of prostate (TURP) and to sum up the nursing experience during operation. Methods: Forty-six cases in the experimental group were performed routine bladder colostomy followed by the drainage rinses and 48 cases in the control group were contacted directly to the flow pipe. The operation time,frequency of intraoperational drainage tube jam and bleeding volume during operation were recorded. Results: The average operation time was 110 minutes in the control group and 90 minutes in the experimental group. Intraoperational drainage tube jam occurred for 96 times in the experimental group and 1 time in the control group. The average bleeding volume was 466 ml in the control group and it was only 46 ml in the experimental group. The difference was significant (P < 0.05). Conclusions: The effect of three-way pipe is satisfactory for drainage in TURP and is easy to popularize.