Abstract: Objective: To discuss the proper surgery time for acute biliary pancreatitis.Methods: Forty-two cases of acute biliary pancreatitis were included in the study.Among them,31 cases received operation within 72 h after admission,6 of whom underwent cholecystectomy,14 were performed cholecystectomy,common bile duct exploration(CBDE) and T tube drainage,and 11 received cholecystectomy,CBDE and T tube drainage as well as pancreatic necrosis clearance and peritoneal cavity drainage.Non-surgical therapy was performed in 11 cases.Results: Among the 11 cases receiving non-surgical therapy,1 case recurred,2 cases died and 1 case developed complications;and among the 31 cases receiving emergency operation,complications occurred in 1 case,and death was observed in no case.Conclusions: Early emergency operation can be performed safely in the majority of cases with acute biliary pancreatitis;active surgical intervention may improve the treatment effect and decrease the recurrence of pancreatitis.