Abstract: Objective: To investigate the bioequivalence of valsartan dispersible tablets and capsules in healthy volunteers.Methods: Twenty volunteers were randomly divided into two groups(test and reference),with double cross-over design.The concentration of valsartan in serum was determined by high performance liquid chromatography(HPLC) and pharmacokinetic parameters were calculated with DAS2.0 practical pharmacokinetics program.Results: The pharmacokinetic parameters of valsartan dispersible tablets and capsules were as follows:t_1/2 were(3.715±1.895)h and(3.585±1.901)h,C_max were(1.797±0.539)μg/ml and(1.848±0.647)μg/ml,T_max were(2.350±0.489)h and(2.425±0.438)h,AUC_{0-36 h} were(10.786±3.794) μg·h^-1·ml^-1 and(10.52±3.96) μg·h^-1·ml^-1.The relative bioavalibility of valsartan dispersible tablets was(111.6±40.7)%.Conclusions: The statistical analysis showed that the test and reference preparation were bioequivalent.