蚌埠地区12所医院医院感染现患率调查及影响因素分析

    Prevalence and risk factors of nosocomial infection in 12 hospitals in Bengbu

    • 摘要:
      目的: 了解蚌埠地区医院感染流行特征及影响因素,为制定有效的医院感染防控措施提供依据。
      方法: 采用床旁调查的方式,对蚌埠地区12家公立医院2021年12月24日00:00—24:00所有病人进行医院感染现患率调查。分析医院感染发生率、感染部位、感染病原菌、抗菌药使用情况及医院感染的影响因素。
      结果: 本研究共调查5 281名住院病人,医院感染现患率为1.14%,最常见的感染部位的呼吸系统(55%),医院感染发生率最高的科室是ICU(9.0%)。感染细菌中以大肠埃希菌和金黄色葡萄球菌居多(均占8.3%),本次调查中抗菌药物使用率为38.6%。多因素logistic回归分析结果显示,病人内在因素中极端年龄、实体肿瘤和昏迷是医院感染发生的独立危险因素(P < 0.01~P < 0.05),外部因素中动静脉插管、泌尿道插管、使用呼吸机、三类手术切口与医院感染的发生风险明显增加(P < 0.01~P < 0.05)。
      结论: 医院感染的主要影响因素有极端年龄、实体肿瘤、昏迷、动静脉插管、泌尿道插管、使用呼吸机和三类手术切口。识别医院感染风险因素,有助于识别高风险人群和高风险因素,可针对性地制定干预措施降低医院感染的发生风险。

       

      Abstract:
      Objective To understand the epidemiological characteristics and influencing factors of nosocomial infection in Bengbu area, and to provide basis for formulating effective prevention and control measures of nosocomial infection.
      Methods A bedside survey was conducted to investigate the prevalence of nosocomial infection among all patients in 12 public hospitals in Bengbu from 0:00 to 24:00 on December 24, 2021. The incidence of nosocomial infection, infection site, infection pathogens, the use of antibiotics and the influencing factors of nosocomial infection were analyzed.
      Results A total of 5 281 hospitalized patients were investigated in this study. The prevalence rate of nosocomial infection was 1.14%, the most common infection site was the respiratory system (55%), and the department with the highest incidence of nosocomial infection was ICU (9.0%). Escherichia coli and Staphylococcus aureus accounted for 8.3% of the infected bacteria, and the use rate of antibiotics in this survey was 38.6%. Multivariate logistic regression analysis showed that extreme age, solid tumor and coma were the independent risk factors of nosocomial infection in the internal factors of patients (P < 0.01 to P < 0.05), while the external factors such as arteriovenous intubation, urinary tract intubation, ventilator use, three types of surgical incision and the risk of nosocomial infection were significantly increased (P < 0.01 to P < 0.05)).
      Conclusion The main influencing factors of nosocomial infection are extreme age, solid tumor, coma, arteriovenous intubation, urinary tract intubation, use of ventilator and three types of surgical incision. Identifying risk factors of nosocomial infection is helpful to identify high-risk groups and factors, and formulate targeted interventions to reduce the risk of nosocomial infection.

       

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