Objective To explore the correlation among acute stress disorder, disease uncertainty and psychological resilience in patients with acute myocardial infarction.

Methods A retrospective analysis was conducted on the data of 102 patients with acute myocardial infarction. The general information, Acute Stress Disorder Scale (ASDS) scores, Disease Uncertainty Scale (MUIS) scores and Resilience Scale (CD-RISC) scores were collected to analyze the relationship among acute stress disorder, disease uncertainty and resilience in patients with acute myocardial infarction.

Results The proportion of patients with acute myocardial infarction who had poor psychological resilience was 74.51% (76/102). The levels of acute stress disorder and disease uncertainty in patients with poor psychological resilience were higher than those in patients with higher psychological resilience (P ＜ 0.05). The ASDS score, MUIS score and CD-RISC score in patients with acute myocardial infarction were (60.16 ± 8.43), (89.50 ± 9.15) and (44.58 ± 14.66), respectively. The results of Pearson correlation analysis showed that the total score and each dimension score of acute stress disorder were positively correlated with those of disease uncertainty (P ＜ 0.01), and the acute stress disorder and disease uncertainty were negatively correlated with psychological resilience, respectively (P ＜ 0.05 to P＜0.01). Taking disease uncertainty as the dependent variable and acute stress disorder as the independent variable, the interval estimation method (non-parametric percentile Bootstrap) was applied for verification, the psychological resilience played a partial mediating effect in the treatment of acute stress disorder and disease uncertainty, and the resulting partial mediating effect value was 0.517, accounting for 71.111% of total effect ratio.

Conclusions The total score and each dimension score of acute stress disorder is positively correlated with those of disease uncertainty. Acute stress disorder and disease uncertainty are negatively correlated with psychological resilience respectively, and acute stress disorder has a mediating effect on disease uncertainty through psychological resilience.