Abstract:
Objective To investigate the incidence rate of chronic hyperkalemia in patients treated with maintenance hemodialysis, and its effects on prognosis of patients.
Methods The basic data of 150 patients treated with maintenance hemodialysis were collected. The patients were divided into the chronic hyperkalemia group (serum potassium >5.0 mmol/L) and non-chronic hyperkalemia group (serum potassium ≤5.0 mmol/L) according to the serum potassium levels after long dialysis intervals. The occurrence of endpoint events and related factors of chronic hyperkalemia in two groups were retrospectively analyzed.
Results There were 56 patients (37.33%) with chronic hyperkalemia. Compared with the non-chronic hyperkalemia group, the incidence of endpoint events was higher (OR = 2.22, 95%CI: 1.067–4.619) (P < 0.05). The results of multivariate regression analysis showed that the diabetes, dialysis frequency (< 3 times/week) and serum phosphorus level were the risk factors of chronic hyperkalemia in MHD patients.
Conclusions The chronic hyperkalemia is common among patients treated with maintenance hemodialysis, and with the increase of blood potassium level, the incidence of endpoint events also gradually increases. Therefore, it is important to actively correct chronic hyperkalemia in patients.