慢性高钾血症对维持性血液透析病人预后的影响

    Effect of chronic hyperkalemia on the prognosis of patients treated with maintenance hemodialysis

    • 摘要:
      目的: 探讨维持性血液透析(MHD)病人慢性高钾血症发病率及其对病人预后的影响。
      方法: 采集血液透析室150例MHD病人的基本资料,根据长透析间隔后血钾水平将病人分为慢性高钾血症组(血清钾>5.0 mmol/L)和非慢性高钾血症组(血清钾≤5.0 mmol/L),回顾性分析2组终点事件发生情况以及慢性高钾血症发生的相关因素。
      结果: 慢性高钾血症病人56例(37.33%),与非慢性高钾血症组相比终点事件发生率较高(OR = 2.22,95%CI:1.067~4.619)(P < 0.05)。多因素回归分析显示,糖尿病、透析频次(<3次/周)、血清磷水平是MHD病人发生慢性高钾血症的危险因素。
      结论: MHD病人中慢性高钾血症较常见,随着血钾水平升高,终点事件发生率也逐渐增高,应积极纠正病人慢性高钾血症。

       

      Abstract:
      Objective To investigate the incidence rate of chronic hyperkalemia in patients treated with maintenance hemodialysis, and its effects on prognosis of patients.
      Methods The basic data of 150 patients treated with maintenance hemodialysis were collected. The patients were divided into the chronic hyperkalemia group (serum potassium >5.0 mmol/L) and non-chronic hyperkalemia group (serum potassium ≤5.0 mmol/L) according to the serum potassium levels after long dialysis intervals. The occurrence of endpoint events and related factors of chronic hyperkalemia in two groups were retrospectively analyzed.
      Results There were 56 patients (37.33%) with chronic hyperkalemia. Compared with the non-chronic hyperkalemia group, the incidence of endpoint events was higher (OR = 2.22, 95%CI: 1.067–4.619) (P < 0.05). The results of multivariate regression analysis showed that the diabetes, dialysis frequency (< 3 times/week) and serum phosphorus level were the risk factors of chronic hyperkalemia in MHD patients.
      Conclusions The chronic hyperkalemia is common among patients treated with maintenance hemodialysis, and with the increase of blood potassium level, the incidence of endpoint events also gradually increases. Therefore, it is important to actively correct chronic hyperkalemia in patients.

       

    /

    返回文章
    返回