Abstract: Objective:To explore an effective therapy for elderly patients with colon cancer complicated with acute intestinal obstruction.Methods:Thirty-seven aged patients with colon cancer complicated with acute intestinal obstruction underwent emergency operation.Twenty-two of the cases were performed one-stage resection and anastomosis,8 cases one-stage resection and anastomosis with proximal colostomy and 5 cases proximal colostomy as well as two-stage resection and anastomosis.Hartmann was observed in 2 cases.Results:All the 37 cases were cured and no preoperative mortality occurred.Postoperative anastomotic leakage was found in 1 case,incision infection in 3 cases,pulmonary infection in 1 case and abdominal infection in 1 case.Conclusions:Early diagnosis,proper perioperative management and cognition of operation indications are essential for treatment of colon cancer complicated with acute intestinal obstruction by one-stage resection and anastomosis.