短暂性脑缺血发作进展至脑梗死的危险因素分析

    Analysis of risk factors for cerebral infarction resulting from transient ischemic attack

    • 摘要: 目的: 探讨短暂性脑缺血发作(TIA)进展至脑梗死的危险因素。方法: 对110例TIA患者临床资料进行回顾性分析。结果: 110例中38例发生了脑梗死,其中椎基底动脉系统TIA90例中28例发生脑梗死,颈内动脉系统TIA15例中8例发生脑梗死,同时累及两个系统者5例发生2例脑梗死,差异无统计学意义(P>0.05)。TIA发作持续>30min、24h内发作5次以上及首次发作后>24h或发作>5次开始治疗的患者发生脑梗死的危险性均增高(P<0.05~P<0.005)。发生脑梗死的TIA患者舒张压、血糖、血胆固醇均高于无脑梗死组(P<0.05~P<0.01)。结论: TIA发作持续时间长、次数多、未及时治疗,尤其伴有高血压、高血糖、高脂血症者短期内发生脑梗死的危险性较高。

       

      Abstract: Objective: To investigate the risk factors for cerebral infarction (CI) resulting from transient ischemic attack (TIA). Methods: The clinical data of 110 hospitalized patients with TIA were evaluated. Results: Thirty-eight patients (34.5%) suffered from cerebral infarction (CI) following TIA in 110 patients. Eight patients with CI resulted from vertebra-basilar artery system, and 28 resulted from internal carotid artery system. There was significantly different in two artery systems (P>0.05). The risks of cerebral infarction were significantly increased in the patients whose syndromes lasted for over 30 min, the patients with 5 attacks within 24 h, the patients who were treated beyond 24 h of syndrome onset, or the treated patients with 5 attacks or more (P<0.05-P<0.005). The high blood pressure, hyperglycaemia and hyperlipoidemia often happened in the patients with CI (P<0.05-P<0.01). Conclusions: The risk is high for the patients to develop CI if patients with TIA last for long time or frequency of attack is much more, or therapy is not yet in time, especially for the patients with high blood pressure, hyperglycaemia and hyperlipoidemia.

       

    /

    返回文章
    返回