儿童紫癜性肾炎急性期血小板参数与肾脏损害的关系

Relationship between platelet parameters on acute hypersensitive purpuric nephritis and kidney damage in children

摘要: 目的: 探讨儿童过敏性紫癜急性期血小板参数与肾脏损害的关系。方法: 应用全自动血细胞计数仪,对51例过敏性紫癜患儿血小板计数(BPC)、血小板平均体积(MPV)、血小板压积(PCT)、血小板分布密度(PDW)进行检测。结果: 过敏性紫癜急性期有肾脏损害组BPC和MPV均明显高于无肾脏损害组(P<0。01)。结论: 血小板参与过敏性紫癜肾脏损害的过程,过敏性紫癜治疗过程中联合抗血小板和抗凝治疗,有可能防止或减轻过敏性紫癜的肾脏损害。

Abstract: Objective: To discuss the correlation between platelet parameters on acute hypersensitive purpura and kidney damage in children.Methods: Blood corpuscle analyser was used to test the blood platelet count(BPC),mean platelet volume(MPV),plateletcrit(PCT) and platelet distribution width(PDW) of 51 children suffering from hypersensitive purpura.Results: The values of PLT and MPV were obviously higher in the group with kidney damage than those in the group without kidney damage BPC during the acute period(P<0.01).Conclusions: Platelet is involved in the process of kidney lesion induced by hypersensitive purpura,so conjoint treatment with anti-platelet and anti coagulation may prevent or alleviate kidney lesion.