六安市健康成人4项凝血指标正常值范围的建立

The establishment of four biological reference intervals of blood coagulation of adults in Lu'an city

摘要: 目的: 通过测定六安市健康成年人群的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT),建立六安市实验室血浆凝血指标的正常值范围.方法: 使用法国STA-compact全自动血凝仪,采用凝固法对300名健康成年人进行PT、APTT、FIB和TT测定.结果: 初步建立六安市健康成人4项凝血指标正常值范围,PT 11.06～14.24 s;APTT 27.57～42.23 s;FIB 1.91～3.99 g/L;TT 14.05～18.47 s.结论: 指标正常值范围对疾病的预防、诊断、疗效及预后均有重要的指导意义,各实验室应制定适合的指标正常值范围.

Abstract: Objective: To detect the levels of prothrombin time(PT),the activated partial thromboplastin time(APTT),plasma fibrinogen(FIB) and thrombin time(TT) of healthy adults in Lu'an city,and establish the biological intervals.Methods: The levels of PT,APTT,FIB and TT in 300 healthy adults were detected by Cluass method using automated blood coagulation analyzer STA-compact.Results: The biological reference intervals of PT,APTT,FIB and TT of healthy adults in Lu'an city were 11.06 to 14.24 s,27.57 to 42.23 s,1.91 to 3.99 g/L and 14.05 to 18.47 s,respectively.Conclusions: The biological reference intervals have important signficances in early prevention and diagnosis,therapeutic effect and prognosis of disease.Each clinical laboratory should formulate the reference intervals.