平阳霉素和曲安奈德治疗血管瘤临床对比研究

    Comparison of effects of intralesional bleomycin A5 and triamcinolone acetonide in treatment of cutaneous hemangioma

    • 摘要: 目的: 寻找治疗血管瘤简单、有效、达到理想美容效果的方法。方法: 将增生期血管瘤随机分为瘤体内注射平阳霉素组和注射曲安奈德组各60例,观察治疗效果和并发症。结果: 平阳霉素的疗效明显优于曲安奈德组(P<0.05),两组的并发症除色素沉着等(P<0.005)外,其余并发症均无统计学意义(P>0.05)。结论: 瘤体内注射平阳霉素是治疗血管瘤安全、有效、简单易行的方法。该方法最大限度地保留了外露部位以及重要功能部位正常的解剖形态和功能,且对其它方法治疗失败的患者仍可治愈,值得临床推广应用。

       

      Abstract: Objective: To find a simple,effective and aesthetic method for the treatment of cutaneous hemangioma in children.Methods: One hundred and twenty children with cutaneous proliferating hemangioma were randomly divided into two groups.Sixty children were treated with intralesional bleomycin A5 hydrochloride injection(1 mg/ml)while 60 children were treated with intralesional triamcinolone acetonide acetate injections(10 mg/ml).The treatment outcome and complications were observed.Results: The cure rate and response rate in the bleomycin group were significantly higher than that of triamcinolone groups(P<0.005).The side effects were different,but not statistically significant.Conclusions: Intralesional bleomycin for the treatment of cutaneous hemangioma in children is very effective,simple and safe.It is better than intralesional triamcinolone acetonide and should be recommended.

       

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