Abstract: Objective: To investigate the diagnosis and treatment of cardiac myxomas.Methods: Twelve cases of cardiac myxoma were diagnosed by the case history,symptoms and auxiliary,examinations including electrocardiogram and echocardiography.All the tumors were removed by moderate hypothermic cardiopulmonary bypass.Results: There was no operative or peri-operative death.The patients didn't show signs of recurrence or metastasis during the follow-up of 1 month to 6 years after operation.Conclusions: Echocardiography plays an important role in the diagnosis of cardiac myxomas.Once the diagnosis is confirmed,the patients should resort to surgical treatment as soon as possible.