安徽省体外膜肺氧合技术开展情况调查研究

    Investigation on the development of extracorporeal membrane oxygenation technology in Anhui province

    • 摘要:
      目的: 调查安徽省体外膜肺氧合(ECMO)技术开展情况,为提高安徽省ECMO应用的能力及质量提供参考。
      方法: 采用横断面调查,由安徽省ECMO质控中心发起,结合国家ECMO技术应用规范和质控指标,设计调查表。调查内容包括:ECMO中心基本信息、ECMO开展现状、ECMO开展学科分布、ECMO技术人员资质、ECMO设备情况、ECMO技术管理情况、ECMO发展建议,对全省已购置ECMO设备的26所医院进行调查。
      结果: 全省开展ECMO技术的医院共计26所,以三级甲等医院为主(88.5%),合肥市数量(8所,30.8%)位居全省首位;2019年前全省ECMO中心主要集中在高校直属医院(85.7%),2019年及其后新增中心主要集中在非高校直属医院(89.4%),全省总体呈逐年上涨趋势;截至调查结束日全省共开展成人ECMO 1 097例,辅助存活率分别为:49.4%(心脏)、49.8%(呼吸)、29.6%(ECPR),总体存活率为46.7%;开展ECMO技术救治病例适应证分布(心脏/呼吸/ECPR)在高校直属医院与非高校直属医院间比较,差异有统计学意义(P < 0.01);不同ECMO适应证的存活率在高校直属医院与非高校直属医院间比较,差异无统计学意义(P > 0.05),但总存活率高校直属医院高于非高校直属医院,差异有统计学意义(P < 0.01);2023年总存活率在开展20例以上的医院与开展小于20例的医院间比较,前者高于后者,差异有统计学意义(P < 0.05);全省开展ECMO技术的学科分布主要为重症医学科(92.3%)、急诊科(19.2%),ECMO设备以进口为主(96.2%);部分医院(19.2%)人员资质不符合国家ECMO技术临床应用管理规范,部分医院(3.8%~15.4%)未健全ECMO技术管理制度;建议需要加大培训力度、提升医疗质量的医院有19所(73.1%);建议需要加强学术交流、分享临床经验的医院16所(61.5%);建议需要提供技术指导、专家下沉或远程会诊等医院15所(57.7%)。
      结论: 安徽省ECMO技术有了一定的发展,但在地区、适应证、学科分布方面不均衡,不同性质、不同规模的医院ECMO总体存活率存在差异,同时在ECMO人员资质、技术管理、培训等方面仍有待加强。

       

      Abstract:
      Objective To investigate the development of extracorporeal membrane oxygenation (ECMO) technology, and provide reference for improving the ability and quality of ECMO application in Anhui Province.
      Methods Using cross-sectional surveys, initiated by the ECMO Quality Control Center of Anhui Province, combined with the national technical application specifications and quality control indicators for ECMO, a survey questionnaire was designed. The survey content included the basic information of ECMO centers, current status of ECMO implementation, distribution of ECMO implementation by academic disciplines, qualifications of ECMO technical personnel, equipment of ECMO, management of ECMO technology and suggestions for the development of ECMO. The survey was conducted on the 26 hospitals that had purchased ECMO equipment in the province.
      Results There were a total of 26 hospitals in the province that carried out ECMO technology, mainly tertiary and first-class hospitals (88.5%), and the number of Hefei (8, 30.8%) ranked the first in the province. Before 2019, the majority of ECMO centers in the province were located in university-affiliated hospitals (85.7%), while after 2019, the majority were located in non-university-affiliated hospitals (89.4%), which showed an overall upward trend year by year in the province. By the end of the survey, 1097 adult ECMO cases had been carried out in the province. The auxiliary survival rate was 49.4% (heart), 49.8% (respiratory), and 29.6% (ECPR), and the overall survival rate was 46.7%. The difference of the indications distribution (heart/respiratory/ECPR) of patients treated with ECMO technology was statistically significant between hospitals directly under the university and those no directly under the university (P < 0.01). There was no statistical significance in the survival rate of different ECMO indications between university hospitals and non-university hospitals (P > 0.05), but the total survival rate of university hospitals was higher than that of non-university hospitals (P < 0.01). In 2023, the total survival rate in hospitals with more than 20 cases was higher than that in hospitals with less than 20 cases (P < 0.05). In the province, the ECMO technology was mainly carried out in critical care medicine (92.3%) and emergency department (19.2%), and the ECMO equipment was mainly imported (96.2%). The personnel qualification of some hospitals (19.2%) did not meet the national management standards for clinical application of ECMO technology, and some hospitals (3.8% ~ 15.4%) did not have a sound ECMO technology management system. There were 19 hospitals (73.1%) that need to strengthen training and improve medical quality; It is suggested that 16 hospitals (61.5%) need to strengthen academic exchanges and share clinical experience. It is suggested that 15 hospitals (57.7%) need to provide technical guidance, expert sinking or remote consultation.
      Conclusions In Anhui Province, ECMO technology has developed to a certain extent, but it is unbalanced in the distribution of regions, indications and disciplines, and the overall survival rate of ECMO in different nature and sizes hospitals is different. Meanwhile, the qualifications of ECMO personnel, technical management and training still need to be strengthened.

       

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