中老年吸烟者肺气肿损害分析

Emphysematous lesion in elderly smokers

摘要: 目的: 观察无症状的中老年吸烟者和不吸烟者的肺气肿损害情况。方法: 选择31名吸烟者和29名从不吸烟者。采用高分辨CT (HRCT)在吸气状态下用1。5mm切片厚度和3cm切片间隔完成检查。由2名X线技术员,通过视觉评估肺气肿损害情况。结果: 肺气肿改变出现在吸烟组中15名(48。4%),而不吸烟组只有1名(3。4%),差异有显著性(P<0。005)。结论: HRCT检查肺气肿损害在无症状吸烟组中是明显的,出现临床症状之前,可以发现早期肺气肿损害。

Abstract: Objective: To study the occurrence of emphysematous lesion in symptom free smokers of about 50 to 60 years of age and non smokers.Methods: A randomized study was conducted in 31 smokers and 29 nonsmokers with high resolution computed tomography(HRCT).HRCT was performed at full inspiration with a 1.5 mm slice thickness and a 3 cm inter-slice distance.Evaluation was made by two radiologists and emphysematous lesions were scored visually.Results: Emphysematous lesions were demonstrated in 15 of the 31 smokers but in only one non smoker.Emphysematous lesions were evident in 48.4% of the healthy symptom free smokers.The difference was significant(P<0.005).Conclusions: HRCT may reveal early emphysematous lesion in smokers before they have any clinical symptoms.