Abstract: Objective: To explore the method of improving the teaching quality of Enzyme Engineering by a serious of effective measures.Methods: A serious of measures was taken to improve the practical and academic quality of Enzyme Engineering teaching,such as optimizing teaching contents,refine teaching methods and means.Results: The students'interesting was improved by optimizing teaching contents and refine teaching methods.Meanwhile,the students'practical ability was improved through carrying out the biological comprehensive experiments.Conclusions: Through the reformation of teaching content and method of Enzyme Engineering,teaching,the students' ability of self-study and mastering knowledge can be improved,and the students' ability to apply comprehensive knowledge and solve practical problems can be enhanced.