Abstract: Objective: To observe the therapeutic effect of endovenous laser treatment (EVLT) combined with high ligation and punctate stripping on simple great saphenous varicosities. Methods: The data of 8 patients (11 lower limbs) who had received EVLT plus high ligation and punctate stripping were retrospectively analyzed. Results: The outcome was satisfactory in all the cases,and the recent symptoms disappeared. No relapse of varicose vein or lower limb swelling was observed during the follow-up of 1-7 months. Two cases (2 lower limbs) had thermal burns of anterior tibial skin and 1 case (1 lower limb) subcutaneous ecchymosis. Conclusions: EVLT combined with high ligation and punctate stripping has affirmed effect in treatment of great saphenous varicosity with the advantage of few complications. It is a safe and reliable minimally invasive therapy.