许力, 陈齐鸣, 韦道祥, 刘晓林, 吴守伟, 胡明洁. Creutzfeldt-Jakob病的临床诊断(附2例报道)[J]. 蚌埠医学院学报, 2008, 33(2): 155-157.
    引用本文: 许力, 陈齐鸣, 韦道祥, 刘晓林, 吴守伟, 胡明洁. Creutzfeldt-Jakob病的临床诊断(附2例报道)[J]. 蚌埠医学院学报, 2008, 33(2): 155-157.
    XU Li, CHEN Qi-ming, WEI Dao-xiang, LIU Xiao-lin, WU Shou-wei, HU Ming-jie. Clinic diagnosis of Creutzfeldt-Jakob disease: Report of 2 cases[J]. Journal of Bengbu Medical College, 2008, 33(2): 155-157.
    Citation: XU Li, CHEN Qi-ming, WEI Dao-xiang, LIU Xiao-lin, WU Shou-wei, HU Ming-jie. Clinic diagnosis of Creutzfeldt-Jakob disease: Report of 2 cases[J]. Journal of Bengbu Medical College, 2008, 33(2): 155-157.

    Creutzfeldt-Jakob病的临床诊断(附2例报道)

    Clinic diagnosis of Creutzfeldt-Jakob disease: Report of 2 cases

    • 摘要: 目的:探讨Creutzfeldt-Jakob病(Creutzfeldt-Jakob disease,CJD)临床早期诊断方法。方法:对2例CJD病患者的临床表现、影像学特点、脑电图改变等资料进行回顾性分析和总结。结果:2例均符合国人CJD临床特点。弥散加权成像(DWI)能检测出特征性病灶,较目前WHO的CJD诊断方法更具敏感性。结论:提高临床医师对本病临床特征性的认识,可以尽早作出正确诊断,减少医源性传播;作为无创性检查的DWI在CJD诊断方法中最具敏感性,临床诊断标准中应考虑DWI检查的列入。

       

      Abstract: Objective: To investigate the early clinical diagnosis of Creutzfeldt-Jakob disease(CJD).Methods: The clinical manifestation,electroencephalogram(EEG) and imaging data of two cases of CJD were analyzed retrospectively.Results: There were special clinical characteristics of CJD in Chinese.The characteristic lesions were detected by diffusion-weighted imaging(DWI) in both of the two cases.DWI was more sensitive than the current clinical diagnosis method suggested by WHO.Conclusions: Recognition of the clinical characteristics of CJD in Chinese is helpful to early and correct diagnosis of the disease and can reduce the iatrogenic transmission.DWI,a non-invasive diagnostic method,is the most sensitive test for the early diagnosis of CJD and consideration should be given to its inclusion in the clinical diagnostic criteria of CJD.

       

    /

    返回文章
    返回