Abstract: Objective: To explore the clinical effect of selective arteria uterine cannula chemotherapy embolism on tubal pregnancy.Methods: Twenty-seven cases of tubal pregnancy were performed arteria uterine visualization with advanced Seldinger technique.The affected arteria uterine was injected methotrexate (one case was injected Fluorouracil) through a catheter and filled with gel foam embolism.The clinical symptoms and signs,serum human chorionic gonadotropin,pelvic hemataocele changes and absorption of pelvic hydrops were observed after the surgery.Results: The arteria uterine cannula was successful in all the 27 cases.Twenty-six of them were cured and 1 failed.The cure rate was 96.3%.No complication occurred.Four patients had healthy babies 3-10 months after the surgery.Conclusions: The new method has the advantages of small wounds and a higher cure rate,which may effectively prevent intraperitonea bleeding,keep the integrity of the arteria uterine and thus retains the fertility.