准分子激光原位角膜磨镶术并发症的预防和治疗

    • 摘要: 目的: 探讨准分子激光原位角膜磨镶术(laser in situ keratom ileusis,LASIK)相关并发症的预防和处理。方法: 对行LASIK治疗的2 259例4 451眼的相关并发症进行总结。结果: 4 451眼术中未出现角膜切穿、洗衣板现象及球结膜严重水肿。出现小角膜瓣和大角膜瓣各1例,游离瓣4例,不全瓣4例,早期球结膜下出血1 335例,眼睑皮肤划伤1 089眼。术后未出现角膜瓣丢失。欠矫的36眼,其中补矫21眼,过矫28眼,回退32眼,眩光667例,夜间驾驶困难111例,激素性高眼压11例,视物有雾状物5例,角膜上皮内生5例,角膜瓣移位3例,中央岛1例,1年后出视网膜脱离1例,感染1例。结论: 应用LASIK治疗近视,严格掌握手术适应证,正确及时识别和处理各种并发症至关重要。

       

      Abstract: Objective: This study was designed to characterize the ultrastructure of the coccoid Helicobacter pylori(H. pylori) forms in the tissues of carcinoma.Methods: Transmission electron microscopy(TEM) technique was used to examine the structure of coccoid H. pylori in 4 cases of gastric carcinoma and 2 cases of esophageal carcinoma.Results: It was found that the coccoid H. pylori were scattered in cancer nest and cancer interspace,some of which enterded cancer cells,macrophages and other cells.The coccoid H. pylori appeared to be similar to the L-forms of other bacteria with varying cell shape and size,different cytoplasmic electron densities and defects in cell wall.Two types of coccoid H. pylori could be distinguished in the tissues of carcinoma by TEM.Type A was smaller with higher electron density in the cytoplasma,and flagellation on the cell membrane,suggesting that it could be viable.However,the type B was larger with lower electron density in the cytoplasma,and no flagellation on the cell membrane,suggesting that it could be a degenerative form.Conclusions: The coccoid forms of H.pulori still have certain degree of viability,thus they may play an important role in the transmission of H. pylori,the relapse of H. pylori related disease after treatment and the development of the related carcinoma.

       

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