马玲, 张竞, 姚婷婷. 复发性卵巢癌治疗方法的选择[J]. 蚌埠医学院学报, 2008, 33(4): 414-415.
    引用本文: 马玲, 张竞, 姚婷婷. 复发性卵巢癌治疗方法的选择[J]. 蚌埠医学院学报, 2008, 33(4): 414-415.
    MA Ling, ZHANG Jing, YAO Ting-ting. Choice of therapy for recurrent ovarian cancer[J]. Journal of Bengbu Medical College, 2008, 33(4): 414-415.
    Citation: MA Ling, ZHANG Jing, YAO Ting-ting. Choice of therapy for recurrent ovarian cancer[J]. Journal of Bengbu Medical College, 2008, 33(4): 414-415.

    复发性卵巢癌治疗方法的选择

    Choice of therapy for recurrent ovarian cancer

    • 摘要: 目的:探讨复发性卵巢癌治疗方法的选择。方法:选择2000~2005年50例复发性卵巢癌,分析其临床病理资料,根据首次治疗情况,复发间隔时间,复发病灶的部位、大小、数量以及患者的一般情况,采用再次减瘤术及术后二线药物化疗、单纯静脉化疗和口服化疗方案治疗。结果:50例患者1、2、3、4、5年总生存率分别为82%、64%、42%、34%、30%。3种治疗方法的1年和3年生存率差异均无统计学意义(P>0.05),而5年生存率差异有统计学意义(P<0.05)。结论:复发性卵巢癌治疗应采用个体化原则,综合评估谨慎选择二次减瘤术,可提高满意减瘤率,改善患者生活质量。

       

      Abstract: Objective: To investigate the choice of treatment for recurrent ovarian cancer.Methods: The clinical pathological data of 50 cases of recurrent ovarian cancer from January 2000 to December 2005 were analyzed.The cases were divided into three groups according to the conditions of their first treatment,the interval time before recurrence,the site,size and number of the recurrent focus,and the patients' general conditions.The three groups were treated by second reductive surgery and postoperative secondline chemotherapy,intravenous chemotherapy and oral chemotherapy,respectively.Results: The survival rate of 1,2,3,4 and 5-year for the 50 patients was 82%,64%,42%,34%,and 30% respectively.Of the three methods,the 1-year and 3-year survival rate had no statistical difference(P>0.05),but the 5-year survival rate was significantly different(P<0.05).Conclusions: Treatment for the recurrent ovarian cancer should be individualized.The second reductive surgery should be selected carefully and evaluated cautiously,which may improve the optimal cytoreductive rate and the patients'life quality.

       

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