陈岭, 邓宏勇, 顾敏晔, 徐宜, 滕斌. 高血压人群胰岛素抵抗相关因素分析[J]. 蚌埠医学院学报, 2011, 36(5): 477-479.
    引用本文: 陈岭, 邓宏勇, 顾敏晔, 徐宜, 滕斌. 高血压人群胰岛素抵抗相关因素分析[J]. 蚌埠医学院学报, 2011, 36(5): 477-479.
    CHEN Ling, DENG Hong-yong, GU Min-ye, XU Yi, TENG Bin. Analysis of insulin resistance related factors among hypertensive population[J]. Journal of Bengbu Medical College, 2011, 36(5): 477-479.
    Citation: CHEN Ling, DENG Hong-yong, GU Min-ye, XU Yi, TENG Bin. Analysis of insulin resistance related factors among hypertensive population[J]. Journal of Bengbu Medical College, 2011, 36(5): 477-479.

    高血压人群胰岛素抵抗相关因素分析

    Analysis of insulin resistance related factors among hypertensive population

    • 摘要: 目的:研究高血压人群胰岛素抵抗相关因素。方法:选自社区高血压203例,进行病史收集、体检及血糖、胰岛素(FIN)及血脂测定,计算胰岛素抵抗指数(HOMA-IR),设定背景人群的上1/4位点(3.71)为切割点,分析不同因素对胰岛素抵抗的影响。结果:病史特点中有无高血压家族史与HOMA-IR间差异无统计学意义(P>0.05);年龄与HOMA-IR呈负相关关系(P<0.01);病程与HOMA-IR无相关关系(P>0.05)。代谢因素中肥胖、高甘油三酯、高血糖与HOMA-IR呈正相关关系(P<0.05)。生活方式中动物性食品摄入量及低运动量与HOMA-IR呈正相关关系(P<0.05)。以FIN为自变量的回归分析发现,体重指数、年龄及收缩压为其影响因素。结论:高血压人群中,各种不同的因素对胰岛素抵抗产生影响。有不良生活习惯及代谢综合征的个体具有显著的胰岛素抵抗。

       

      Abstract: Objective: To explore the insulin resistance related factors among hypertensive population.Methods: Two hundred and three hypertensive patients in community were included in this study;The medical history,physical examination data,the levels of fasting plasma glucose,fasting insulin(FIN),triglyceride(TG) and high density lipoprotein cholesterol of the patients were tested;setting the background population of 1/4 point(3.71) as the cutting point,the effect of different factors on insulin resistance index(HOMA-IR) was analyzed after the HOMA-IR was calculated.Results: The family history of hypertension and the course of disease had no correlation to HOMA-IR(P>0.05),but the age of patients had negatively correlation to HOMA-IR(P<0.01).Among the metabolism factors,obesity,high TG and glucose have positive correlation to HOMA-IR(P<0.05).About the life styles,the intakes of animal foodstuff and low amounts of exercise have positive correlation to HOMA-IR(P<0.05).In the regression analysis,BMI,age and systolic pressure were the influence factors,when the FIN was set as the independent variable.Conclusions: Among the hypertensive population,different risk factors had different impacts on IR.Significant insulin resistance was usually related to individuals with bad life styles and metabolic syndrome. More

       

    /

    返回文章
    返回