Abstract: Objective: To assess the value of OMOM capsule endoscopy in the diagnosis of small intestine diseases.Methods: Ninety patients who would receive capsule endoscopy were divided into group A(health check volunteers,n=6),group B(with unexplained abdominal pain or diarrhea,n=53)and group C(with obscure gastrointestina1 bleeding,n=31).The capsule endoscopy data of those patients were collected and analyzed.Results: No complaints or complications were observed during the tests;86 patients underwent the capsule endoscopy successfully;58 cases of small intestinal lesions were found in the 90 cases;the total positive rate of capsule endoscopy was 64.4%(58／90);the positive rates of group B and group C were 64.7%(33／52)and 83.3%(25／30),respectively.Conclusions: The OMOM capsule endoscopy has the advantages of simple operation,high safety and no lesion.It is of great value in diagnosis of unexplained abdominal pain,diarrhea and obscure gastrointestinal bleeding,and can be the first choice for diagnosis of small intestinal diseases.