桑更生, 冯燕娴, 石增刚, 丁中. 2型糖尿病患者颈动脉内膜中层厚度及冠状动脉病变的观察[J]. 蚌埠医学院学报, 2007, 32(6): 675-677.
    引用本文: 桑更生, 冯燕娴, 石增刚, 丁中. 2型糖尿病患者颈动脉内膜中层厚度及冠状动脉病变的观察[J]. 蚌埠医学院学报, 2007, 32(6): 675-677.
    SANG Geng-sheng, FENG Yan-xian, SHI Zhen-gang, DING Zhong. Relationship between intima media thickness of carotid and coronary heart disease in patients with type 2 diabetes mellitus[J]. Journal of Bengbu Medical College, 2007, 32(6): 675-677.
    Citation: SANG Geng-sheng, FENG Yan-xian, SHI Zhen-gang, DING Zhong. Relationship between intima media thickness of carotid and coronary heart disease in patients with type 2 diabetes mellitus[J]. Journal of Bengbu Medical College, 2007, 32(6): 675-677.

    2型糖尿病患者颈动脉内膜中层厚度及冠状动脉病变的观察

    Relationship between intima media thickness of carotid and coronary heart disease in patients with type 2 diabetes mellitus

    • 摘要: 目的: 观察2型糖尿病患者颈动脉内膜中层厚度(IMT)及冠状动脉病变情况,探讨其间关系。方法: 182例2型糖尿病中未伴发冠状动脉病变(A组)58例,以及根据冠状动脉造影(CAG)检查显示伴发冠状动脉病变(B组)124例;B组中稳定型心绞痛(SAP)组60例,不稳定型心绞痛(UAP)组64例;正常对照组133例。检测其IMT及斑块,同时测定其血糖、血脂、体重指数等,比较IMT及斑块发生率。结果: 2型糖尿病患者的IMT值显著增高,3组间差异有统计学意义(P<0.01),B组平均IMT值不仅较正常对照组增厚(P<0.01),且较A组亦增厚(P<0.01)。UAP组与SAP组的Gensini积分和IMT值差异无统计学意义(P>0.05),UAP组不稳定型斑块发生率高于SAP组(P<0.0167)。结论: 颈动脉超声可直接测量动脉的厚度及斑块性质,为判断和预测2型糖尿病患者的冠脉病变提供了重要参考价值。

       

      Abstract: Objective: To observe the relations between intima media thickness(IMT) of common carotid and coronary heart disease in elderly patients with type 2 diabetes mellitus.Methods: One hundrend and twenty-four type 2 diabetes mellitus patients with coronary heart diseases including 60 cases of SAP and 64 cases of UAP(group A),58 patients without coronary heart diseases as manifested by CAG(group B) and 133 healthy subjects were enrolled in our study.The IMT of the 3 groups was observed with high resolution ultrasound,and the levels of blood pressure,plasma glucose and blood lipids were measured as well.The factors affecting IMT were analyzed.Results: The IMT in the 3 groups was statistically different(P<0.01).Gensini and IMT in both UAP and SAP groups had no statistical differences(P>0.05).The rate of unstable carotid plaque of all patients in UAP group was higher than that in SAP group(P<0.0167)Conclusions: Ultrasonography could determine the IMT of carotid and carotid plaque,so it is of great value in predicting coronary heart diseases in type-2 diabetes mellitus patients.

       

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