氧驱动雾化吸入布地奈德、盐酸氨溴索治疗毛细支气管炎疗效观察

袁增权

氧驱动雾化吸入布地奈德、盐酸氨溴索治疗毛细支气管炎疗效观察

袁增权

Effect of oxygen atomized inhalation of pulmicort repule and ambroxol on infants with bronchiolitis

YUAN Zeng-quan

摘要

摘要: 目的:观察氧驱动雾化吸入布地奈德、盐酸氨溴索治疗毛细支气管炎的临床疗效。方法:将93例毛细支气管炎患儿随机分为治疗组48例和对照组45例。在常规治疗的基础上,治疗组采用氧驱动雾化吸入布地奈德混悬液0.5 mg、盐酸氨溴索15 mg加生理盐水2 ml,每天2次;对照组采用α-糜蛋白酶3 mg、地塞米松2 mg加生理盐水20 ml超声雾化吸入,每天2次;疗程5~7天。观察2组患者临床症状、体征消失的时间。结果:观察组临床症状和肺部哮鸣音消失时间、治疗时间明显短于对照组(P < 0.05~P < 0.01)。治疗组总有效率为93.75%,对照组为80.00%,差异有统计学意义(P < 0.01)。结论:布地奈德、盐酸氨溴索氧驱动雾化吸入治疗小儿急性毛细支气管炎疗效显著,值得推广。

Abstract: Objective: To observe the clinical effect of oxygen atomized inhalation of pulmicort repule ambroxol in treatment of infants with bronchiolitis. Methods: Ninety-three infants with bronchopneumonia were randomly divided into two groups. The treatment group (48 cases) were administered oxygen atomized inhalation of pulmicort repule 0.5 mg,ambloxoi 15 mg and NS 2 ml twice a day,while the control group (45 cases) were treated with ultrasonic atomized inhalation of α-chymotrpsin 3 mg,DXM 2 mg and NS 20 ml twice a day. The clinical symptoms were observed. Results: The disappearing time of the clinical symptoms,wheezing rale and the mean therapy time of the treatment group were shorter than those of the control group (P < 0.05-P < 0.01). The overall response rates of the treatment group and the control group were 80.00% and 93.75%, respectively. The difference was significant (P < 0.01). Conclusions: The therapy of oxygen atomized inhalation of pulmicort repule and ambroxol is effective on infants with bronchiolitis,and is worth spreading

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