急性脑梗死患者C反应蛋白水平的变化及其临床意义

Clinical significance of changes of serum level of C-reactive protein in patients with acute cerebral infarction

摘要: 目的: 探讨急性脑梗死患者血清C反应蛋白(C-reactiveproteinCRP)水平的变化及其与脑梗死严重程度的关系。方法: 测定63例急性脑梗死患者和24名健康人血清CRP的含量,按脑卒中患者临床神经功能缺损程度评分(NDS)标准对患者进行评分,分组比较。结果: 脑梗死组血清CRP水平明显高于正常对照组(P<0.001)。脑梗死轻、中、重型患者血清CRP水平差异有统计学意义(P<0.01)。结论: 血清CRP水平增高与脑梗死的发生和严重程度有密切关系。

Abstract: Objective: To investigate the changes of the serum level of C-reactive protein(CRP) in patients with acute cerebral infarction and its relationship to the severity of cerebral infarction.Methods: The serum level of CRP in 63 patients and 24 healthy persons was determined.All the patients were scored by clinic neurological deficit scale(NDS),and compared in groups.Results: The serum level of CRP in the patients was significantly higher than that in normal controls(P<0.01) and it was significantly higher in the serious group than in the middle and mild groups(P<0.01).Conclusions: The serum level of CRP is closely correlated with the severity of cerebral infarction.