Abstract: Objective: To evaluate the therapeutic effects of uterine artery embolization on hysteromyoma and its influence on ovarian function.Methods: The embolization agents were injected into the bilateral uterine arteries of 46 patients with hysteromyoma using the Seldinger technique via the percutaneous femoral arterial catheterization.All patients were followed up for 3 to 6 months.The clinical symptoms,volume of uterus and hysteromyoma and ovarian endocrine function in all cases were observed before and after interventional therapy.The volume of uterine and hysteromyoma and level of hormone(E2,FSH and LH) of ovary were measured before and after uterine artery embolization.Results: The uterine artery embolization in 46 patients were successful,the symptoms of all cases were significantly improved.The average volumes of uterus and hysteromyoma were(325.9±43.61) cm³ and(57.4±19.47) cm³ before treatment,respectively.The volumes of uterus and hysteromyoma shrunk 40.1% & 38.5% and 52.0% & 67.2% in 3 and 6 months after embolization,respectively,the differences of which were statistically significant(P<0.01).The differences of the levels of E2,FSH and LH between before and after treatment were not statistically significant(P>0.05).Conclusions: Uterine artery embolization can significantly improve the clinical symptoms and shrink the volumes of uterus and hysteromyoma,which does not affect the physiological function of ovary.