Abstract: Objective: To study the hospital disposition of Candida infection and its drug resistance to frequently used antifungal agents so as to provide medication basis for clinical application.Methods: Seventy cases infected with Candida were analyzed retrospectively.Results: Of the 70 cases,Monilia albicans accounted for 61.43%,slick Monilia 21.43%,Candida tropicalis 11.43 and Candida Krusei 5.71%.The four frequently used antifungal agents which had drug resistence to Candida were,flucytosine,amphotericin,fluconazole and itracozole.The high risk divisions were lung department,ICU and Cadre ward.The risk factors included serious foundation disease,virulence operation and irrational use of antibiotics.Conclusions: Flucytosine and amphotericin are excellent antibacterial to Candida.It is essential to strengthen the management of high risk divisions so as to prevent hospital infection.