过敏性紫癜73例临床分析

    Clinical analysis of 73 cases of allergic purpura

    • 摘要: 目的: 分析过敏性紫癜发病季节性、诱发因素、内脏损害及多种临床表现和相关鉴别要点。方法: 对73例患者临床资料回顾性分析。结果: 2~4月份发病者47%,10~12月份发病者30%。36%的患者发病前有明显的上呼吸道感染史。腹痛占47%,血便占29%,关节痛占33%,血尿占14%,蛋白尿占34%。转氨酶增高8%,ECG异常者8%。结论: 过敏性紫癜好发于冬春季节,上呼吸道感染可能是过敏性紫癜最常见及复发的原因。腹型紫癜,尤其是腹痛在前、紫癜在后者应与外科急腹症相鉴别。关节型以关节疼痛、肿胀为主,主要累及踝、膝关节。肾型紫癜应及时检查尿常规及随访观察,确定有无紫癜性肾炎的存在。

       

      Abstract: Objective: To discuss the clinical features of allergic purpura.Methods: Seventy-three patients with allergic purpura were analyzed retrospectively.Results: Of the 73 cases,47% of the allergic purpura occurred in February,March and April,and 30% in October,November and December.36% of the patients had a history of upper respiratory tract infection in the early days.47% of the cases presented abdominal pain,29% hematochezia,33% joint pain,14% hematuria and 34% proteinuria.The serum level of ALT was increased in 8% of patients and change of ECG was observed in 8% of the patients.Conclusions: Allergic purpura occurs more frequently in the spring and winter.Upper respiratory tract infection may be the common risk factor for the reoccurrence of allergic purpura,so treatment of upper respiratory tract infection should be emphasized.Gastrointestinal purpura with abdominal pain ahead of purpura should be distinguished from acute abdomen deceases.Arthritic purpura was often involved with symptoms of the knees or the ankles.Nephritis purpura was usually associated with proteinuria or hematuria,so routine urine detection should be conducted.

       

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