血清孕酮在早期异位妊娠中的诊断价值

    • 摘要: 目的: 探讨血清孕酮在早期异位妊娠的临床应用价值。方法: 比较64例异位妊娠和72例正常宫内妊娠者在治疗前血清孕酮值的变化;有35例药物治疗和8例期待疗法,比较两者血清孕酮和β-hCG值下降的程度。结果: 64例异位妊娠者孕酮值为(30.31 ±21.20) nmol/L,72例宫内妊娠者血清孕酮值为(82.54 ±23.95) nmol/L,两者差异有统计学意义(P<0.001);当血清孕酮取临界值为69.96 nmol/L时,诊断异位妊娠灵敏度100%,阴性预测价值100%。患者血清孕酮下降至正常的时间明显短于β-hCG下降至正常的时间(P<0.001)。结论: 血清孕酮测定诊断早期异位妊娠具有特异性强、敏感性高的优点。

       

      Abstract: Objective: This study was designed to characterize the ultrastructure of the coccoid Helicobacter pylori(H. pylori) forms in the tissues of carcinoma.Methods: Transmission electron microscopy(TEM) technique was used to examine the structure of coccoid H. pylori in 4 cases of gastric carcinoma and 2 cases of esophageal carcinoma.Results: It was found that the coccoid H. pylori were scattered in cancer nest and cancer interspace,some of which enterded cancer cells,macrophages and other cells.The coccoid H. pylori appeared to be similar to the L-forms of other bacteria with varying cell shape and size,different cytoplasmic electron densities and defects in cell wall.Two types of coccoid H. pylori could be distinguished in the tissues of carcinoma by TEM.Type A was smaller with higher electron density in the cytoplasma,and flagellation on the cell membrane,suggesting that it could be viable.However,the type B was larger with lower electron density in the cytoplasma,and no flagellation on the cell membrane,suggesting that it could be a degenerative form.Conclusions: The coccoid forms of H.pulori still have certain degree of viability,thus they may play an important role in the transmission of H. pylori,the relapse of H. pylori related disease after treatment and the development of the related carcinoma.

       

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