Abstract: Objective: To study the characteristics and reasons of recurrent diabetic ketoacidosis(DKA) in Uighur patients with type-2 diabetes in Xinjiang hotan region.Methods: The clinical data of 37 Uighur and 16 Han patients with recurrent DKA in hotan area were analyzed.The patients' age,genders,course of the disease,blood glucose levels,glycosylated hemoglobin A1c(HbAlc) levels,blood pressure,blood total cholesterollevels,triglyceride(TG) levels,high density ripoprotein,low density lipoprotein,blood urea nitrogen(BUN),creatinine,pH,carbon diaxide combining powere(CO₂CP),and serum creatine kinase(CK)were collected and analyzed.Results: There were significant differences between the two groups in the course of DKA,HbA1c,TG,BUN,CK,pH and CO₂CP(P<0.05 to P<0.01).The recovery time of ketone,pH,insulin dosage every day and the hospital stay of the Uighur diabetes group exceeded those of the Han patients group(P<0.05 to P<0.01).The alimentary control in Uighur diabetes group was poorer than that in Han patients group(P<0.01).Conclusions: The condition of recurrent DKA is more serious in Uighur diabetes patients than in Han patients,and the recovery is slower.The characteristics of recurrent uygur DKA should be considered and the diabetes diet guidance strengthened in hotan area.Only in this way,can the poor control of diabetes in the area be improved.