Abstract: Objective: To investigate the value of Color Doppler Ultrasound in the diagnosis of varicocele for guiding clinic.Methods: The Color Doppler data of 50 cases with varicocele were retrospectively analyzed.The inside diameter and reflux time of varicocele and testicular volume in all patients were recorded at quiet breathing and standing after Valsalva action,which was compared with healthy people.Results: Compared with the control group,the inside diameter of varicocele widened obviously(P<0.01).The varicocele contorted and presented grid,its reflux time lengthened after Valsalva action(P<0.01).The left testis volume of the patients shrunk obviously(P<0.01),the left varicocele was the most common.Conclusions: Color Doppler ultrasound is convenient,cheap,fast,repeatable and accurate in diagnosing varicocele,which is an important index in clinical therapy.