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    慢性阻塞性肺疾病患者血清甲状腺素动态观察的意义

    Significance of change of thyroid hormone in the serum of patients with chronic obstructive pulmonary disease

      摘要
    • 摘要: 目的: 观察慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者急性加重期和治疗后稳定期的血清甲状腺激素变化。方法: 对39例COPD急性加重期患者,于入院时和治疗2周后分别检测血清甲状腺素(T4)、游离T4(FT4)、三碘甲状腺原氨酸(T3)、游离T3(FT3)及促甲状腺激素(TSH)含量,并与对照组比较。结果: 入院时COPD组血清中T3、FT3、T4均较对照组显著下降(P<0.01),治疗2周后36例病情缓解者上述指标均明显上升(P<0.01),病情加重的3例无回升。结论: 动态观察血清甲状腺激素的变化,对COPD急性加重期患者的病情判断及预后具有一定的临床参考价值。

       

      Abstract: Objective: To observe the change of thyroid hormone in the serum of patients with chronic obstructive pulmonary disease(COPD) at the acute stage and the stationary phase.Methods: The levels of T3,FT3,T4,FT4 and TSH in the serum of 39 patients with COPD were detected before treatment and two weeks after treatment,and the results were compared with those of the controls.Results: The levels of T3,FT3,T4 in the serum of patients with COPD were lower than those of the controls(P<0.01).After treatment,the above levels decreased significantly in 36 cases(P<0.01),but did not in 3 severe cases.Conclusions: The dynamic change of thyroid hormone in the serum of patients with COPD is of value for the judgment of the prognosis of the patients.

       

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