血清总胆汁酸测定对鉴别肝硬化及消化性溃疡并发上消化道出血的意义

Discrimination of complicated hemorrhage of liver cirrhosis and peptic ulcer by serum total bile acid

摘要: 目的:探讨血清总胆汁酸测定对鉴别肝硬化失代偿及消化性溃疡并发上消化道出血的意义。方法:回顾性分析71例肝硬化及消化性溃疡并发上消化道出血患者,并选择40名健康体检者为正常对照组,比较各组总胆汁酸水平。结果:肝硬化失代偿并发上消化道出血患者血清总胆汁酸(30.75±28.70)μmol/L,显著高于消化性溃疡并发上消化道出血患者的(4.80±3.87)μmol/L及正常对照组的(4.50±3.60)μmol/L(P<0.01)。结论:血清总胆汁酸测定可作为鉴别肝硬化及消化性溃疡并发上消化道出血的一种简单指标。

Abstract: Objective: To investigate the role of serum total bile acid in discriminating complicated hemorrhage of liver cirrhosis and peptic ulcer.Methods: The clinical data of 71 patients with complicated hemorrhage of liver cirrhosis or peptic ulcer were analyzed retrospectively,and 40 normal people acted as control subjects.Results: The mean serum total bile acid of the patients with decompensated cirrhosis complicated with hemorrhage(30.75±28.70) μmol/L was significantly higher than that of the patients with peptic ulcer complicated with hemorrhage(4.80±3.87) μmol/L and the control(4.50±3.60) μmol/L(P<0.01).Conclusions: It is simple and effective to discriminate liver cirrhosis and peptic ulcer complicated with hemorrhage by serum total bile acid.