Abstract: Objective: To discuss the management of acute limb ischemia. Methods: One hundred and twenty-six cases with acute limb ischemia that including 84 case of arterial embolism and 42 case of arterial thrombosis were analyzed. According to Rutherford criteria,there were 13 cases in category Ⅰ,107 cases in category Ⅱ and 6 cases in category Ⅲ,respectively. Cases in category Ⅰ were adopted medical treatment,while in category Ⅱ,cases were mainly adopted surgical and/or interventional treatments,and cases in Ⅲ were amputated. Results: There were 6 deaths in category Ⅱ and Ⅲ within 30 days after treatments. Eleven cases were amputated. One hundred and twenty cases were recovered. The follow-up period was from 1 to 72 months. Conclusions: Expeditious diagnosis and immediate effective treatment,combined by alleviating reperfusion injury are key points in improving therapeutic effect of acute limb ischemia and reduce morbidity and mortality.