Objective To discuss the knowledge, attitude, behavior and knowledge demand of vaccination for left-behind and non-left-behind child guardians and targeted intervention mode.

Methods Sixty-four physical examination rural left-behind children (group A) and 64 non-left-behind children (group B) from December 2016 to December 2018 were selected.The present situation of child vaccination rate were investigated using the children vaccination card, and the knowledge, attitude and behavior of vaccination and knowledge demand and targeted intervention mode of children's guardians were understood using the way of questionnaire.

Results Among 128 children, 93 (72.65%) children were vaccinated with basic vaccines throughout the course, which included 34 left-behind children (36.56%) and 59 non-left-behind children (63.44%).The vaccination rates of 3 times vaccination rates of hepatitis B vaccine and polio vaccine, JE vaccine, DPT (Diphtheria, Pertussis, Tetanus) vaccine, and group A epidemic cerebrospinal meningitis vaccine in non-left-behind children were higher than those in left-behind children (P < 0.05 to P < 0.01).All child guardians for the vaccination knowledge of the questionnaire designing had a good understanding, and the correct recognition rates of "know which two vaccine are needed for birth", "know the effect of vaccination", and "know when children start to vaccination" in guardians of group B children were higher than those in guardians of group A children (P < 0.05).There was no statistical significance in the correct recognition rate of other 7 items of vaccination knowledge between the guardians of two groups (P>0.05).Among the 5 vaccination behaviors and needs, the proportion of "believe that the vaccination place is too far away" in guardians of children in group A was higher than that of guardians of children in group B (P < 0.01), while the differences of the remaining 4 items in guardians of children between two groups were not statistically significant (P>0.05).

Conclusion Arousing the enthusiasm of village vaccination staff is the focus of preventive intervention for left-behind children.It is suggested that the peer education should be introduced into the families of left-behind children to carry out corresponding propaganda and education, to strengthen the care and input to the vaccination work of left-behind children.