Abstract:
Objective:To study the relationship between the level of plasma homocysteine(Hcy) and subcortical small vessel disease(SVD), and the clinical significance.
Methods:The levels of plasma Hcy in 90 cases with cerebral SVD(including lacunar infarction and white matter lesion) diagnosed by MRI(SVD group) and 90 hospitalized patients without SVD(control group) were compared.
Results:The levels of plasma Hcy in SVD group were significantly higher than those in control group(
P<0.01).
Conclusions:The level of plasma Hcy increasing is an independent risk factor of cerebral SVD.