Abstract: Objective:To investigate the perioperative nursing experience of severe chronic heart failure patients treated with cardiac resynchronization therapy(CRT) or cardiac resynchronization therapy-cardioverter defibrillator(CRT-D).Methods:The data of the preoperative, intraoperative and postoperative nursing in 8 chronic heart failure patients treated with CRT or CRT-D were retrospectively analyzed.Results:The operations in 5 patients treated with CRT, 2 patients treated with CRT-D and 1 patient treated with CRT-D were unsuccessful, and then treated with implantable cardioverter defibrillator ICD were successful.Compared with before treatment, the cardiac function and ejection fraction of all cases were improved after treatment(P<0.01).The QRS wave becoming narrow and no cardiac tamponade, electrode dislocation and incision non-healing in all patients were found, the acute left heart failure in 1 case and incision blood effusion in 1 case were found.Conclusions:The CRT or CRT-D for treating chronic intractable heart failure is an effective means, the perioperative good care is an important means to get better effects.