Abstract: Objective:To explore the effects of clinical pathway on patients with hypertension using Meta analysis.Methods:The application effects of the clinical pathway method and traditional treatment method on patients with hypertension were investigated by screening CNKI,VIP,Wanfang database and CBMdisc.Through the strict quality evaluation,all data were analyzed by using Rev Man5.1 software.Results:Two thousand and eighty-three objects from 15 documents were selected,which were divided into the clinical path way group(1 035 cases) and traditional treatment group(1 048 cases).The Meta-analysis results showed that the differences of the length of hospital stayWMD=-3.15,95%CI(-4.64~-1.65),P<0.01,hospitalization expensesWMD=-615.70,95%CI(-648.03~-583.38),P<0.01,satisfaction degree of patientsRR=1.26,95%CI(1.21~1.30),P<0.01,knowledge of healthRR=1.29,95%,CI(1.22~1.37),P<0.01,systolic blood pressureWMD=-13.97,95%CI(-16.47~-11.47),P<0.01,diastolic blood pressureWMD=-4.70,95%CI(-5.82~-3.59),P<0.01 and compliance behaviorRR=1.24,95%CI(1.19~1.28),P<0.01 between two groups were statistically significant.Conclusions:The effect of clinical path way in the application of patients with hypertension is better than that of traditional treatment.Because of the large differences of the quality of the documents and large samples,the design need more rigorous,and randomized controlled trial can be used to confirm this conclusion.