糖尿病足溃疡危险因素分析

汪睿; 吴坚

doi:10.13898/j.cnki.issn.1000-2200.2015.11.011

糖尿病足溃疡危险因素分析

汪睿,
吴坚

Analysis of risk factors for diabetic foot ulcer

WANG Rui,
WU Jian

摘要

摘要: 目的:探讨糖尿病足(dibatic foot,DF)溃疡发生的危险因素,为预防及延缓DF溃疡的发生、发展提供参考依据。方法:收集DF溃疡住院患者201例,糖尿病无DF溃疡住院患者302例。对相关临床资料、实验室检测指标进行分析。结果:Logistic回归分析提示,男性、诊断时间、红细胞沉降率、纤维蛋白原、C反应蛋白、胱抑素C、糖化血红蛋白和脂蛋白(a)均为DF溃疡的危险因素(P<0.05~P<0.01)。其中男性、诊断时间、红细胞沉降率、C反应蛋白、胱抑素C均为独立危险因素(P<0.05~P<0.01)。结论:对于有危险因素的或已经发现糖尿病或DF溃疡的患者,应该积极控制血糖,合理抗感染、抗凝、降纤维蛋白原以及适当的营养支持等综合治疗。

Abstract: Objective: To explore the risk factors for diabetic foot(DF) ulcers and provide reference for the prevention and delay of the occurrence of DF ulcers.Methods: Two hundred and one cases of hospitalized patients with DF ulcers and 302 cases with non-DF ulcers were collected in the study.SPSS 22.0 software was used for statistical analysis of the related dinical data and laboratory fest index.Results: Logistic regression analysis showed that male,levels of erythrocyte sedimentation rate,fibrinogen,C-reactive protein,cystatin C,glycated hemoglobin,lipoprotein(a)and uric acid were the risk factors for DF ulcers(P<0.05 to P<0.01),among which male,diagnosis time,levels of erythrocyte sedimentation rate,C-reactive protein and cystatin C were independent risk factors(P<0.05 to P<0.01).Conclusions: Comprehensive treatment including control of blood glucose,anti-infection,anticoagulant,fibrinolysis and proper nutrition support are essential for patients with diabetes or diabetic foot ulcer.

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