二维超声联合四维超声在胎儿畸形诊断中的应用
The application of two-dimensional ultrasound combined with four-dimensional ultrasound in the diagnosis of fetal malformation
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摘要: 目的:探讨二维超声联合四维超声检查(下称联合超声检查)在胎儿畸形诊断中的临床应用。方法:选取产前检查孕妇5050例,孕20~28周。首先对胎儿进行常规二维超声检查,对怀疑有畸形的胎儿再进行联合超声检查,并根据引产、分娩或到上级医院进一步检查结果进行对比分析,评价其诊断符合率。结果:5050例孕妇共分娩5064例胎儿,其中双胎14例,单纯二维超声检查发现畸形87例,联合超声检查发现畸形117例,经临床证实的胎儿畸形124例,联合超声检查诊断正确率为94.4%,明显高于单纯二维超声诊断正确率70.2%(P<0.01)。结论:在胎儿畸形诊断中采用联合超声检查,能有效地提高诊断准确性,降低缺陷患儿的出生率,具有较高的临床应用价值。Abstract: Objective:To investigate the clinical value of two-dimensional ultrasound combined with four-dimensional ultrasound in the diagnosis of fetal malformation.Methods:Five thousand and fifty pregnant women detected by two-dimensional ultrasound combined with four-dimensional ultrasound, pregnancy 20 to 28 weeks were investigated.The fetus was examined using two-dimensional ultrasonography, the fetus suspected with malformation was additionally examined using four-dimensional ultrasound.The data of the induced abortion, delivery and further examination results from superior hospital were analyzed to evaluate the diagnosis coincidence rate.Results:Five thousand and sixty-four fetuses(including 14 cases twin) born by five thousand and fifty pregnant women included 87 cases malformation detected by two-dimensional ultrasonography and 117 cases malformation detected by two-dimensional ultrasound combined with four-dimensional ultrasound.The diagnosis coincidence rate of two-dimensional ultrasound combined with four-dimensional ultrasound(94.4%) was significantly higher than that of two-dimensional ultrasound(70.2%)(P<0.01).Conclusions:The two-dimensional ultrasound combined with four-dimensional ultrasound can effectively improve the accurate rate of diagnosis, and reduce the birth rate of defect child, which has high clinical value.