Abstract: Objective: To investigate the cognition of speciality and career intention of undergraduates in general practice(GP) medicine. Methods: The cognition of speciality and career intention of GP undergraduates from Bengbu Medical College were investigated using questionnaire survey. Results: One hundred and twenty(42.4%)GP students were willing to learn the general medicine-related courses, 104 students were satisfied with the teaching arrangement of GP. The proportions of students pursuing general practice medicine master's degree education and general practitioners participating the standardized training were 42.9% and 39.6%, respectively. One hundred and eight students were willing to be a general practitioner after graduation, the main reasons included 26(24.1%) students thinking the direction of general medicine as the future development direction, and 21(19.4%) students thinking job stability of general practitioner. The 30.6% of students were unwilling to be a general practitioner after graduation. The 23(30.7%) students thought that the income of general practitioner was low, and 19(25.3%) students thought that the social status of general practitioner was low. Conclusions: The cognition of speciality and career intention of undergraduates in general practice need to be further improved, national policies should tilt to general practitioner. Medical colleges should strengthen general practice education and guide students to plan career correctly.