Abstract: Objective: To investigate the clinical significance of fetal electrocardiogram in the diagnosis of high-risk pregnancy.Methods: The fetal electrocardiogram in 130 high-risk pregnant women with 32 to 42 gestational weeks and 60 normal pregnant women with the same gestational age were examined,the result of which was analyzed.Results: The incidence of abnormal fetal electrocardiogram in high-risk pregnant women(49.23%) was significantly higher than that in normal pregnant women(11.67%)(P < 0.01).The main manifestations of abnormal fetal electrocardiogram were tachycardia(42.19%),ST segment change(18.75%),arrhythmia(17.19%) and bradycardia(15.63%),the composition difference of abnormal fetal electrocardiogram in all cases was not statistically significant(P > 0.05).Conclusions: The periodic testing of fetal electrocardiogram in high-risk pregnant women can early find the fetal distress and hypoxia,reduce the incidence of neonatal asphyxia,and reduce the birth rate of disabled children.