Abstract:
Objective: To study the drug sensitivity of L-forms of
Pseudomonas aeruginosa(PA) to the third and forth generation cephalosporins.
Methods: PA was induced into a stable L-form.The drug sensitivity of PA L-forms to the third and forth generation cephalosporins was analyzed by K-B drug sensitivity test.The change trend of drug sensitivity and resistance of PA L-forms was analyzed.
Results: The inhibition zone of PA L-forms was smaller than that of their parent bacteria,and there had the significant difference(
P<0.05).But the drug sensitivity of L-forms of PA to the third and forth generation cephalosporins was still sensitive.
Conclusions: The drug sensitivity of PA L-forms to the third and forth generation cephalosporins is still sensitive.