李甲, 姚晓玲, 郑岚. 血培养阳性标本细菌分布及耐药性分析[J]. 蚌埠医学院学报, 2016, 41(10): 1360-1362. DOI: 10.13898/j.cnki.issn.1000-2200.2016.10.033
    引用本文: 李甲, 姚晓玲, 郑岚. 血培养阳性标本细菌分布及耐药性分析[J]. 蚌埠医学院学报, 2016, 41(10): 1360-1362. DOI: 10.13898/j.cnki.issn.1000-2200.2016.10.033
    LI Jia, YAO Xiao-ling, ZHENG Lan. Analysis of the distribution and drug resistance of pathogens in positive blood culture specimens[J]. Journal of Bengbu Medical College, 2016, 41(10): 1360-1362. DOI: 10.13898/j.cnki.issn.1000-2200.2016.10.033
    Citation: LI Jia, YAO Xiao-ling, ZHENG Lan. Analysis of the distribution and drug resistance of pathogens in positive blood culture specimens[J]. Journal of Bengbu Medical College, 2016, 41(10): 1360-1362. DOI: 10.13898/j.cnki.issn.1000-2200.2016.10.033

    血培养阳性标本细菌分布及耐药性分析

    Analysis of the distribution and drug resistance of pathogens in positive blood culture specimens

    • 摘要: 目的:了解血培养阳性标本中分离的病原菌分布及耐药情况,为临床合理使用抗生素提供治疗依据。方法:回顾分析2014年7月至2015年6月临床送检血培养标本中分离的病原菌及药敏试验结果,采用BACT/ALERT 3D型全自动血培养仪进行培养,ATB微生物分析系统进行细菌鉴定和药敏试验。结果:从临床送检的血培养标本中共分离出病原菌76株,其中革兰阳性菌41株,革兰阴性菌31株,真菌4株,分别占53.95%、40.79%和5.26%。前5位病原菌为凝固酶阴性葡萄球菌、大肠埃希菌、金黄色葡萄球菌、肺炎克雷伯菌和铜绿假单胞菌。大肠埃希菌和克雷伯菌属对碳氢酶烯类药物敏感率为100%,未发现耐万古霉素革兰阳性球菌。结论:及时监测血培养病原菌变化及耐药趋势,对指导临床用药至关重要。

       

      Abstract: Objective: To investigate the distribution and drug resistance of pathogens isolated from blood culture to provide the basis in clinical rational use of antibiotics.Methods: The data of the pathogens isolated from blood culture and results of drug sensitive test were retrospectively analyzed from July 2011 to June 2012.The blood was cultured using the BACT/ALERT 3D automatic blood culture instrument.The bacteria identification and drug sensitive test were implemented using ATB expression identification system.Results: Seventy-six strains of pathogenic bacteria were isolated from clinical blood culture samples,which included 41 strains of gram-positive bacteria(53.95%),31 strains of gram-negative bacteria(40.79%) and 4 strains of fungi(5.26%).The top five pathogens were the Coagulase-negative staphylococci,Escherichia coli,staphylococcus aureus,Klebsiella pneumonia and Pseudomonas aeruginosa by turn.The sensitive rate of Escherichia coli and Klebsiella penumonia to carbapenem drug was 100%,the gram-positive Cocci of vancomycin-resistant was not found.Conclusions: The timely monitoring of the pathogenic bacteria change in blood culture and trend of drug resistance are important in guiding the clinical drug use.

       

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