Abstract: Objective: To observe the influences of Qili cardiac capsule on the liver,renal function and electrolyte levels in patients with chronic heart failure(CHF).Methods: Eighty-two patients with CHF were randomly divided into the control group(38 cases) and observation group(44 cases).The control group were treated with the routine treatment of digoxin,and the observation group were additionally treated with Qili cardiac capsule based on the control group.The treatment course in two groups was 4 weeks.The liver,renal function and electrolyte level between two groups were compared.Results: The clinical efficacy in observation group was better than that in control group(P<0.05).The differences of the renal function indexes(including creatinine,urea and uric acid) and electrolyte levels between two groups were not statistically significant(P>0.05).The levels of aspartate aminotransferase and total bile acid of liver function indexes and cystatin C,retinol-binding protein of renal function indexes in observation group were significantly higher than those in control group(P<0.01).The levels of albumin,prealbumin and calcium,sodium and chloride of electrolytes in observation group were lower than those in control group(P<0.05 to P<0.01).The liver,renal function and electrolyte levels in two groups were in normal scope.Conclusions: Based on the routine treatment,the curative effects of additional Qili cardiac capsule on CHF are good,which has certain effects on the liver,renal function and electrolyte levels,and no adverse effect.