Abstract: Objective: To explore the effects of low temperature adjustable sodium dialysis mode on hypotension in middle-elderly patients.Methods: Ten hypotension for ≥2 times middle-elderly patients treated with regularly hemodialysis for continuous 4 times were divided into the standard group(treatment with standard dialysis mode) and low temperature group(treatment with low temperature adjustable sodium dialysis mode),and two groups were treated for 4 weeks,12 times each mode.The body temperature,heart rate,and blood pressure and heart rate at 30-minute intervals during the process of dialysis were monitored before and after dialysis.The times of hypotension,related symptoms and nurse intervention in two groups were recorded.Results: The incidence of hypotension and times of nurse intervention in low temperature group were significantly less than those in standard group(P<0.01).During and after dialysis,the systolic and diastolic pressure in low temperature group were obviously higher than those in standard group(P<0.01).Conclusions: Lower temperature adjustable sodium dialysis can effectively reduce the occurrence of hypotension,and improve the tolerance to dialysis in middle-elderly patients,which is a safe and effective therapy.