Abstract: Objective:To explore the application value of the ultrasonography in early locating diagnosis of uterus cornea pregnancy and tubal interstitial pregnancy.Methods:The ultrasonographic characteristics of uterus cornea pregnancy and tubal interstitial pregnancy in 41 cases were analyzed.All patients were followed up.Results:Among 41 patients,the uterus cornea pregnancy in 27 cases and interstitial pregnancy in 14 cases were identified.Thirty-five cases were rightly diagnosed,the accuracy rate of which was 85.37%(35/41).Among 27 cases with uterus cornea pregnancy,24 cases were operated,and 3 cases were converted to intrauterine pregnancy,which included 2 cases of early abortion,and 1 case of term birth and postpartum placental retention.Fourteen cases with interstitial pregnancy were treated with laparoscopic operation.Conclusions:The ultrasonography in locating diagnosis of uterus cornea pregnancy and tubal interstitial pregnancy has high accuracy,transvaginal sonography can improve the accuracy of differential diagnosis,which play important guiding significance for the choice of clinical treatment.